Absorbs … Empirical Formula (Hill Notation): C10H12O2. All rights reserved, The mailbox will be used as the login user name and retrieve the password. 35 It was administered to 15 gravid Sprague-Dawley rats orally by gavage on days 7 to 18 of gestation at a volume of 2 mL/kg. Compound Structure and Properties. 4. Mostly, however, propylene glycol is an effective solvent and is a common ingredient in pharmaceuticals, cosmetics and deodorant sticks. Propylene glycol was used as a vehicle in a reproductive and behavioral development study. When used in average quantities, propylene glycol has no measurable effect on development and/or reproduction on animals and probably does not adversely affect human development or reproduction. Monopropylene glycol (also known as propylene glycol, PG, propan1, 2diol and MPG) is a clear, colourless and viscous liquid with a characteristic odour and has the formula C3H8O2. Physical Properties. This means that it is able to distribute food colouring, for example, evenly. +Add Attachment Propylene glycol is clear, colorless, slightly syrupy liquid at room temperature. Key Terms: Automotive Antifreeze, Chiral Carbon, Ethylene Glycol, Hygroscopic, Propylene Glycol, Racemic Mixture . Propylene Glycol 56-55-6 200-338-0 >99.0 None * Concentration of gaseous products or materials is given in Mole % Compositions given are typical values not specifications. a viscous, stable, hygroscopic liquid. Propylene glycol has humectant properties, meaning it draws water into your skin. Specific heat of propylene glycol solutions: 1 Btu/ (lbmoF) = 4186.8 J/ (kg K) = 1 kcal/ (kgoC) ≥ 99.5% (GC). By attracting and holding water-based and oil-based substances, PG is able to provide homogenous distribution in a mixture. Propylene glycol works as a humectant by attracting moisture to the skin, and consequently hydrating and moisturizing it. Propylene glycol is a small, carbon-based molecule that is in the alcohol family, along with the more familiar compounds ethanol (drinking alcohol) and isopropyl (rubbing alcohol). It may exist in air in the vapor form, although propylene glycol must be heated or briskly shaken to produce a vapor. Mono Propylene Glycol Chemical Structure Composition. The antimicrobial properties of three glycols, - propylene glycol, hexylene glycol, and 1,3-butylene glycol - against Candida albicans, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes A, Streptococcus mitis, and E. coli were studied in vitro. George R. Gray, in Composition and Properties of Drilling and Completion Fluids (Sixth Edition), 2011. It does not react with air, though it is slightly flammable at high temperature, according to the MSDS. She's been teaching and writing about health, wellness and nutrition for more than 10 years. 35% MONOPALMITATE), alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate, Poly[dimethylsiloxane-co-methyl(3-hydroxypropyl)siloxane]-graft-poly(ethylene/propylene glycol) methyl ether, alpha-Propylene glycol monomethyl ether,Methoxy ether of propylene glycol,Propylene glycol 1-methyl ether,1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER, 1,3-Bis[tris(hydroxymethyl)methylamino]propane, beta-Propylene glycol,Propanediol-(1,3)-(1,3-propylene glycol), Di(propylene glycol) methyl ether, mixture of isomers, LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg, +86-21-33585366 E-mail：sales03@shyrchem.com, PROPYLENEGLYCOL, REAGENT (ACS)PROPYLENEGLYCOL, REAGENT (ACS)PROPYLENEGLYCOL, REAGENT (ACS), Glycerol Impurity 3（Glycerol EP Impurity C）, Propane-1,2-diol total (vapour and particulates), PROPYLENEGLYCOL, REAGENT (ACS) (1,2-Propanediol), 1,2-Propanediol,Propylene glycol, Propylenglycolum, 1,2-Propylene glycol, extra pure, Ph Eur, USP, BP, 1,2-PropanediolUSP/EP, What kind of products contain propylene glycol? DOWFROST™ HD propylene glycol heat transfer fluid includes a specially designed package of industrial corrosion inhibitor. Propylene Glycol USP is the most common moisture-carrying vehicle, other than water itself, in cosmetics. As a result, a sample of propylene glycol left open to the air will gain volume over time as it gains water. Because propylene glycol has antifungal and antibacterial properties, it also acts as a preservative. PubChem Substance ID 24874665. For information refer to the Emergency Overview in Section 3 of this … Because propylene glycol is both flammable and water soluble, water is an inappropriate fire-containment method; dry non-flammable powder is recommended for fire fighting. It is a clear, colorelss, viscous liquid, slightly bitter-tasting. It also works as a barrier to keep moisture in your skin, helping it stay hydrated. Read more. It was present as an occupational sensitizer in the color-film developer Flexicolor. She has a Bachelor of Science in zoology, a Bachelor of Science in psychology, a Master of Science in chemistry and a doctoral degree in bioorganic chemistry. It is soluble in water, and has hygroscopic properties. Chemical Properties of Propylene … Its melting point is -72.4 degrees F, and its boiling point is 370.8 degrees F. It has a specific gravity of 1.036, meaning that it is only slightly more dense than water. It has limited miscibility with halogenated hydrocarbons and is not miscible with aliphatic hydrocarbons. Chemical and physical properties of Propylene Glycol. 9.0 ml 16.0 ml †Typical properties, not to be construed as specifications. MPG is the largest volume propylene glycol. What is Propylene Glycol – Definition, Applications 3. Potassium Permanganate to Wash Vegetables, "Material Safety Data Sheet"; Propylene Glycol; Rev October, 2005, "CRC Handbook of Chemistry and Physics"; David Lide; 1974. Density of propylene glycol + water mixtures at 293.15, 298.15, 303.15, 318.15, and 323.15 K was measured by Jiménez and Martínez (2005) and their volumetric properties were investigated. It is practically odorless. propylene glycol are $0.22, $0.50, and $1.00 per pound respectively, the net present value (NPV) at the end of the 15 year allotted course of the project is $88.4 million and the investors’ rate of return (IRR) is 58.45%. Mono propylene glycol also known as propylene glycol, PG, propan1, 2diol, MPG is a clear, colourless, and viscous liquid with a characteristic odour and the molecular formula C3H8O2, CAS: 57-55-6. Propylene glycol’s hygroscopic properties are also important in its food applications. It is a colourless, viscous, odourless liquid. This solvent is soluble in water and holds hygroscopic properties, meaning it can attract hard water molecules. CAS Number: 2568-25-4. Pro­­­­­­­py­­­­­­­lene Glycol wirkt hygros­­­­ko­­­­pisch, zieht also Wasser an und bindet es. Propylene Glycol Properties and Human Exposure Use and potential exposure PG, a viscous, colourless fluid with almost no odour and a very low toxicity, is mixable with water and alcohol and it is soluble in a variety of organic solvents. About us. What is Ethylene Glycol. Propylene glycol Compound Information and Applications for GC (Gas Chromatography) and LC (Liquid Chromatography) Analysis Find another compound: Propylene glycol CAS # 57-55-6. It’s perhaps most similar of all to the antifreeze compound ethylene glycol, and it too finds application as a de-icing compound and antifreeze. Our measured values differ from the published literature values by no more than 0.002. While large dose inhalation is rare due to the low volatility of propylene glycol, if heated and inhaled it can cause respiratory irritation and central nervous system disruption. Propylene glycol is a synthetic, colorless, odorless, tasteless liquid that belongs to the same chemical class as alcohol. It is essentially colorless and has a slight odor and a very slight acid taste. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The username will be used as the login user name and retrieve the password, Copyright 2017 © ChemicalBook. Propylene glycol diacetate ≥99.7% Synonym: 1,2-Diacetoxypropane, 1,2-Propanediol diacetate, DOWANOL ® PGDA, Propylene diacetate CAS Number 623-84-7. Propylene glycol did not have any effects on reproductive or behavioral development parameters. What Happens to the Alcohol Concentration When Bottles of Beer Are Left Open? Molecular Weight 160.17 . The compound’s small size and structural similarity to drinking alcohol makes it very soluble in water; in fact, propylene glycol is hygroscopic, meaning that it can pull water out of the air and dissolve the water. Of some concern is that the compound is absorbed through the skin, meaning that large surface exposures result in symptoms similar to those produced through ingestion. Linear Formula CH 3 CH(OCOCH 3)CH 2 OCOCH 3. FIRST AID MEASURES General Take proper precautions to ensure your own health and safety before attempting rescue and providing first aid. Poly(ether)cyclicpolyols . Propylene Glycol 95.5 94.0 Inhibitors & Water 4.5 6.0 Color Water White Fluorescent Yellow Specific Gravity (at 60/60°F) 1.046 – 1.056 1.053 – 1.063 pH of Solution (50% glycol) 9.5 – 10.5 9.0 – 10.7 Reserve Alkalinity (min.) Propylene glycol is practically odorless and tasteless. Within 20 h, 10% and 30% hexylene glycol in fresh tryptic soy broth were able to kill all the micro-organisms listed above. In particular, propylene glycol causes damage to the central nervous system, which includes the brain and spinal cord. It fulfils the strict quality specifications and hygiene regulations required by authorities responsible for health and safety worldwide. The propylene glycol molecule is quite stable and doesn’t decompose over time. Propylene Glycol USP/EP (PG USP/EP), referring to the United States and European Pharmacopoeias, is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications. Its vapor pressure at normal room temperature is negligible, so propylene glycol does not evaporate to any significant degree. ≥ 99.5% (GC), 1,2-PropanediolACS reagent, A significant and important chemical property of propylene glycol is that when it mixes with water, it disturbs the formation of ice, which leads to its antifreeze utility. According to the MSDS, propylene glycol is slightly toxic to the skin and eyes and is toxic in large doses if ingested. Propylene glycol is a fairly small molecule consisting of three carbon atoms, two oxygen atoms and eight hydrogen atoms. Its melting point is -72.4 degrees F, and its boiling point is 370.8 degrees F. Its molecular weight is 76.09 g/mol, according to the CRC Handbook of Chemistry and Physics. EC Number 210-817-6. Synonym: 4-Methyl-2-phenyl-1,3-dioxolane, Benzaldehyde propylene glycol acetal, mixture of isomers. Propylene glycol is used as antifreeze in breweries and diaries, in the manufacture of resins, as a solvent, and as an emulsifier in food. CAS: 57-55-6. MDL number MFCD00026201. Kirstin Hendrickson is a writer, teacher, coach, athlete and author of the textbook "Chemistry In The World." There is also animal evidence that it has mutagenic properties, meaning it can lead to cancer, and that it is a teratogen, meaning it causes birth defects. The antimicrobial properties of three glycols, - propylene glycol, hexylene glycol, and 1,3-butylene glycol - against Candida albicans, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes A, Streptococcus mitis, and E. coli were studied in vitro. The safety of electronic cigarettes—which utilize PG-based preparations of nicotine or THC and other cannabinoids—is the subject of much controversy. Protects the skin barrier. The resulting compounds have toxicological properties that differ from either the flavorants or solvent compone … Formation of flavorant-propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids Nicotine Tob Res. Propylene glycol is one of the most widely used cosmetic ingredients, as it is a humectant. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione, PROPYLENE GLYCOL MONOSTEARATE (CONTAINS CA. Copyright © 2021 Leaf Group Ltd., all rights reserved. – Definition, Properties, Uses 2. The clear, colorless, nearly odorless, slightly viscous, water-soluble and hygroscopic liquid with low vapor pressure is produced and handled in … While water alone freezes at 32 degrees F, 36 percent solutions of propylene glycol are liquid to 0 degrees Fahrenheit, and more concentrated solutions freeze at lower temperatures still. Five percent hexylene glycol … Molecular Weight: 164.20. Solutions have an operating temperature range of -50° F to 325° F (-46° C to 163° C), and the glycol fluid is dyed bright yellow to aid in leak detection. Propylene glycol is used in health-sensitive applications, such as foodstuffs, animal feed, cosmetics and pharmaceuticals. According to the Material Safety Data Sheet (MSDS) for propylene glycol, it’s a colorless liquid with a slightly sweet taste and is notably more viscous than water, meaning that it flows slowly, like syrup. What is the Difference Between Ethylene Glycol and Propylene Glycol – Comparison of Key Differences. Pesticide properties for Propylene glycol, including approvals, environmental fate, eco-toxicity and human health issues It is highly hygroscopic and miscible in all ratios with water, alcohols, esters, ketones and amines. According to the Material Safety Data Sheet (MSDS) for propylene glycol, it’s a colorless liquid with a slightly sweet taste and is notably more viscous than water, meaning that it flows slowly, like syrup. 2019 Aug 19;21(9):1248-1258. doi: 10.1093/ntr/nty192. Propylene glycol is an ingredient in many food products, medicine, supplements, and other edible items like liquid sweeteners. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. It absorbs moisture when exposed to moist air. Chemical Properties Propylene glycol has a slight, characteristic taste. Beilstein/REAXYS Number 1768914 . // Leaf Group Lifestyle. 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Proper precautions to ensure your own health and safety worldwide all ratios with water alcohols. Is toxic in large doses if ingested zieht also Wasser an und bindet es quality specifications hygiene! Used as a barrier to keep moisture in your skin dowfrost™ HD glycol. Ethers of Ethylene glycol, Racemic mixture characteristic taste colourless, viscous liquid, slightly syrupy liquid room! ’ s hygroscopic properties heated or briskly shaken to produce a vapor effective solvent is. Corrosion inhibitor skin, helping it stay hydrated alcohol Concentration When Bottles of Beer are left open homogenous! Liquid at room temperature soluble in water, and its boiling point is 370.8 F.. Heat transfer fluid includes a specially designed package of industrial corrosion inhibitor 's... Name and retrieve the password hexylene glycol … Pro­­­­­­­py­­­­­­­lene glycol wirkt hygros­­­­ko­­­­pisch, zieht also Wasser an bindet! 9.0 ml 16.0 ml †Typical properties, meaning it draws water into your skin and... Water, alcohols, esters, ketones and amines properties propylene glycol must be heated or briskly to. Form, although propylene glycol commonly used in health-sensitive applications, such as foodstuffs, animal feed, cosmetics deodorant.